1,2,5,6-Tetrahydro-3-pyridinecarboxylic Acid Hydrochloride
Guvacine Hydrochloride
CAS: 6027-91-4
Molecular Formula: C6H10ClNO2
1,2,5,6-Tetrahydro-3-pyridinecarboxylic Acid Hydrochloride - Names and Identifiers
1,2,5,6-Tetrahydro-3-pyridinecarboxylic Acid Hydrochloride - Physico-chemical Properties
| Molecular Formula | C6H10ClNO2 |
| Molar Mass | 163.6021 |
| Melting Point | 316 °C (decomp) |
| Solubility | H2O: soluble |
| Appearance | white solid |
| Color | white |
| Storage Condition | Inert atmosphere,Room Temperature |
| MDL | MFCD00055191 |
| Physical and Chemical Properties | Soluble in methanol, ethanol, DMSO and other organic solvents, derived from the palm plant Areca catechu L. seeds. |
| In vitro study | Guvacine hydrochloride is a potent inhibitor of GABA transporter, dispalys modest selectivity for cloned GABA transporters with IC 50 s of 14 μM (human GAT-1), 39 μM (rat GAT-1), 58 μM (rat GAT-2), 119 μM (human GAT-3), 378 μM (rat GAT-3), and 1870 μM (human BGT-3). Guvacine has low affinity at hBGT-1 (IC 50 >1 mM). Guvacine hydrochloride is a potent inhibitor of GABA uptake, but does not inhibit sodium-independent GABA binding, and is weak or inactive as a GABA receptor agonist. Guvacine inhibits the uptake GABA and β-alanine with IC 50 s of 23 ± 2 μM, 66 ± 11 μM in the Cat spinal cord, and 8 ± 1 μM, 123 ± 28 μM in the rat cerebral cortex, respectively. |
1,2,5,6-Tetrahydro-3-pyridinecarboxylic Acid Hydrochloride - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
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Spot supply
Product Name: Guvacine Hydrochloride Visit Supplier Webpage Request for quotationCAS: 6027-91-4
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Guvacine Hydrochloride Visit Supplier Webpage Request for quotationCAS: 6027-91-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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